Symmetric Uncertainty-Aware Feature Transmission for Depth Super-Resolution

Color-guided depth super-resolution (DSR) is an encouraging paradigm that enhances a low-resolution (LR) depth map guided by an extra high-resolution (HR) RGB image from the same scene. Existing methods usually use interpolation to upscale the depth maps before feeding them into the network and transfer the high-frequency information extracted from HR RGB images to guide the reconstruction of depth maps. However, the extracted high-frequency information usually contains textures that are not present in depth maps in the existence of the cross-modality gap, and the noises would be further aggravated by interpolation due to the resolution gap between the RGB and depth images. To tackle these challenges, we propose a novel Symmetric Uncertainty-aware Feature Transmission (SUFT) for color-guided DSR. (1) For the resolution gap, SUFT builds an iterative up-and-down sampling pipeline, which makes depth features and RGB features spatially consistent while suppressing noise amplification and blurring by replacing common interpolated pre-upsampling. (2) For the cross-modality gap, we propose a novel Symmetric Uncertainty scheme to remove parts of RGB information harmful to the recovery of HR depth maps. Extensive experiments on benchmark datasets and challenging real-world settings suggest that our method achieves superior performance compared to state-of-the-art methods. Our code and models are available at https://github.com/ShiWuxuan/SUFT.Comment: 10 pages, 9 figures, accepted by the 30th ACM International Conference on Multimedia (ACM MM 22

Generalizable Heterogeneous Federated Cross-Correlation and Instance Similarity Learning

Federated learning is an important privacy-preserving multi-party learning paradigm, involving collaborative learning with others and local updating on private data. Model heterogeneity and catastrophic forgetting are two crucial challenges, which greatly limit the applicability and generalizability. This paper presents a novel FCCL+, federated correlation and similarity learning with non-target distillation, facilitating the both intra-domain discriminability and inter-domain generalization. For heterogeneity issue, we leverage irrelevant unlabeled public data for communication between the heterogeneous participants. We construct cross-correlation matrix and align instance similarity distribution on both logits and feature levels, which effectively overcomes the communication barrier and improves the generalizable ability. For catastrophic forgetting in local updating stage, FCCL+ introduces Federated Non Target Distillation, which retains inter-domain knowledge while avoiding the optimization conflict issue, fulling distilling privileged inter-domain information through depicting posterior classes relation. Considering that there is no standard benchmark for evaluating existing heterogeneous federated learning under the same setting, we present a comprehensive benchmark with extensive representative methods under four domain shift scenarios, supporting both heterogeneous and homogeneous federated settings. Empirical results demonstrate the superiority of our method and the efficiency of modules on various scenarios

An Empirical Study of CLIP for Text-based Person Search

Text-based Person Search (TBPS) aims to retrieve the person images using natural language descriptions. Recently, Contrastive Language Image Pretraining (CLIP), a universal large cross-modal vision-language pre-training model, has remarkably performed over various cross-modal downstream tasks due to its powerful cross-modal semantic learning capacity. TPBS, as a fine-grained cross-modal retrieval task, is also facing the rise of research on the CLIP-based TBPS. In order to explore the potential of the visual-language pre-training model for downstream TBPS tasks, this paper makes the first attempt to conduct a comprehensive empirical study of CLIP for TBPS and thus contribute a straightforward, incremental, yet strong TBPS-CLIP baseline to the TBPS community. We revisit critical design considerations under CLIP, including data augmentation and loss function. The model, with the aforementioned designs and practical training tricks, can attain satisfactory performance without any sophisticated modules. Also, we conduct the probing experiments of TBPS-CLIP in model generalization and model compression, demonstrating the effectiveness of TBPS-CLIP from various aspects. This work is expected to provide empirical insights and highlight future CLIP-based TBPS research.Comment: 13 pages, 5 fiugres and 17 tables. Code is available at https://github.com/Flame-Chasers/TBPS-CLI

Self-delivery of N-hydroxylethyl peptide assemblies to the cytosol inducing endoplasmic reticulum dilation in cancer cells

Inspired by clinical studies on alcohol abuse induced endoplasmic reticulum disruption, we designed a N-hydroxylethyl peptide assembly to regulate the ER stress response in cancer cells. Upon coupling with a coumarin derivative via an ester linkage, a prodrug was synthesized to promote esterase-facilitated self-delivery of N-hydroxylethyl peptide assemblies around the ER, inducing ER dilation. Following this, ER-specific apoptosis was effectively and efficiently activated in various types of cancer cells including drug resistant and metastatic ones

Heterogeneous Federated Learning: State-of-the-art and Research Challenges

Federated learning (FL) has drawn increasing attention owing to its potential use in large-scale industrial applications. Existing federated learning works mainly focus on model homogeneous settings. However, practical federated learning typically faces the heterogeneity of data distributions, model architectures, network environments, and hardware devices among participant clients. Heterogeneous Federated Learning (HFL) is much more challenging, and corresponding solutions are diverse and complex. Therefore, a systematic survey on this topic about the research challenges and state-of-the-art is essential. In this survey, we firstly summarize the various research challenges in HFL from five aspects: statistical heterogeneity, model heterogeneity, communication heterogeneity, device heterogeneity, and additional challenges. In addition, recent advances in HFL are reviewed and a new taxonomy of existing HFL methods is proposed with an in-depth analysis of their pros and cons. We classify existing methods from three different levels according to the HFL procedure: data-level, model-level, and server-level. Finally, several critical and promising future research directions in HFL are discussed, which may facilitate further developments in this field. A periodically updated collection on HFL is available at https://github.com/marswhu/HFL_Survey.Comment: 42 pages, 11 figures, and 4 table

Federated Learning for Generalization, Robustness, Fairness: A Survey and Benchmark

Federated learning has emerged as a promising paradigm for privacy-preserving collaboration among different parties. Recently, with the popularity of federated learning, an influx of approaches have delivered towards different realistic challenges. In this survey, we provide a systematic overview of the important and recent developments of research on federated learning. Firstly, we introduce the study history and terminology definition of this area. Then, we comprehensively review three basic lines of research: generalization, robustness, and fairness, by introducing their respective background concepts, task settings, and main challenges. We also offer a detailed overview of representative literature on both methods and datasets. We further benchmark the reviewed methods on several well-known datasets. Finally, we point out several open issues in this field and suggest opportunities for further research. We also provide a public website to continuously track developments in this fast advancing field: https://github.com/WenkeHuang/MarsFL.Comment: 22 pages, 4 figure

Enzyme-mediated dual-targeted-assembly realizes a synergistic anticancer effect

We designed and synthesized homochiral-peptide-based boron diketonate complexes. Co-administration of the two stereoisomers in cancer cells led to molecular assembly targeting both the plasma membrane and the lysosomes mediated via membrane-bonded enzymes. The dual-targeted-assembly generates a synergistic anticancer effect with amplified cancer spheroid toxicity and enhanced inhibition efficacy on cancer cell migration